Science Based Nutrition

January 24, 2010

Vitamin D supplementation can reduce falls in nursing care facilities

Giving people living in nursing facilities vitamin D can reduce the rate of falls, according to a new review. This finding comes from a study of many different interventions used in different situations. In hospitals, multifactorial interventions and supervised exercise programs also showed benefit.

December 31, 2009

Putting limits on vitamin E

Filed under: Main Content — Tags: , , , , — ScienceDaily: Nutrition News @ 3:00 pm
Scientists have done the most comprehensive and accurate study of clinical data on vitamin E use and heart disease to date, and it warns that indiscriminate use of high-dose vitamin E supplementation does more harm than good.

December 6, 2009

Antioxidant compound reduced incidence of colorectal metachronous adenomas

Filed under: Main Content — Tags: , , , , , , , , — ScienceDaily: Vitamin News @ 10:00 pm
Supplementation with a selenium-based antioxidant compound decreased the risk of developing new polyps of the large bowel -- called colorectal metachronous adenomas -- in people who previously had colorectal polyps removed.

July 20, 2009

Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults [Vitamins, minerals, and phytochemicals]

Background: Limited observational evidence suggests lower antioxidant concentrations in individuals with the metabolic syndrome (MetS); few randomized controlled trials have addressed the effect of multiple antioxidants on the risk of MetS.

Objective: The objective was to examine the effect of antioxidant supplementation for 7.5 y on the incidence of MetS and the epidemiologic association between baseline serum antioxidant concentrations and the prospective risk of MetS.

Design: Adults (n = 5220) participating in the SUpplementation en VItamines et Minéraux AntioXydants (SU.VI.MAX) primary prevention trial were randomly assigned to receive a supplement containing a combination of antioxidants (vitamins C and E, β-carotene, zinc, and selenium) at nutritional doses or a placebo. Subjects were free of MetS at baseline and were followed for 7.5 y.

Results: Antioxidant supplementation for 7.5 y did not affect the risk of MetS. Baseline serum antioxidant concentrations of β-carotene and vitamin C, however, were negatively associated with the risk of MetS; the adjusted odds ratios (and 95% CIs) for the highest compared with the lowest tertile were 0.34 (0.21, 0.53; P for trend = 0.0002) and 0.53 (0.35, 0.80; P for trend = 0.01), respectively. Baseline serum zinc concentrations were positively associated with the risk of developing MetS; the adjusted odds ratio (and 95% CI) for the highest compared with the lowest tertile was 1.81 (1.20, 2.72; P for trend = 0.01).

Conclusions: The experimental finding of no beneficial effects of antioxidant supplementation in a generally well-nourished population is consistent with recent reports of a lack of efficacy of antioxidant supplements. However, the relations observed between the risk of MetS and baseline serum antioxidant concentrations, which probably reflect associations with overall dietary patterns, do support the current recommendations to consume antioxidant-rich foods. This trial was registered at clinicaltrials.gov as NCT00272428.

June 16, 2009

Study Suggests Vitamin D Screening And Appropriate Supplementation Indicated For All Cancer Patients

Vitamin D deficiency was found to be prevalent in cancer patients regardless of nutritional status, according to the results of a recent study conducted at Cancer Treatment Centers of America (CTCA). Based on these results, CTCA researchers determined that screening for vitamin D deficiency and aggressive vitamin D repletion should be considered for all people with cancer.
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